Risk factors for the type of scoliosis in which the cause is unknown include:

Family history
1/3 of parents, siblings, or children of people with scoliosis of unknown cause have spinal curvatures of 10 degrees or more 2.

If both parents have scoliosis of unknown cause, the possibility it may develop in their children Risk factors for the type of scoliosis in which the cause is unknown include:

Family history
1/3 of parents, siblings, or children of people with scoliosis of unknown cause have spinal curvatures of 10 degrees or more 2.
If both parents have scoliosis of unknown cause, the possibility it may develop in their children increases by 50% 8.
Scoliosis with larger curves occurs about 5 times more frequently in females than males.

In addition, scoliosis of unknown cause is seen in as many as 16% of people with heart disease at birth (congenital heart disease), and it is more common in people with:
Abnormal kyphosis
Forward displacement of a spinal bone, usually in the lower back (spondylolisthesis)
Missing or abnormally short limb(s)

Other disorders related to the tissue development while in the womb (embryonic connective tissue disorders)by 50% 8.
Scoliosis with larger curves occurs about 5 times more frequently in females than males.

In addition, scoliosis of unknown cause is seen in as many as 16% of people with heart disease at birth (congenital heart disease), and it is more common in people with:

Abnormal kyphosis
Forward displacement of a spinal bone, usually in the lower back (spondylolisthesis)
Missing or abnormally short limb(s)
Other disorders related to the tissue development while in the womb (embryonic connective tissue disorders)

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